A Microsoft file hosting and synchronization service.
Yes. Since your goal is to let OneDrive manage and synchronize the Windows Pictures folder, the safest approach is to disable iCloud Photos on that PC before enabling OneDrive Pictures backup.
Do not simply delete the iCloud Photos folder while iCloud Photos app is still enabled. This can end up deleting your photos from all devices.
I would do this first:
Confirm your photos are available at iCloud.com or on another Apple device.
- If there are any photos you want to keep an extra local copy of on this Windows device, open iCloud Photos in File Explorer, right-click them and select Always keep on this device. Once they are fully downloaded, copy them to another folder or an external drive.
- Open iCloud for Windows (this is the app)
Go to Photos and turn off iCloud Photos. Also turn off Shared Albums if it is enabled.
Click Done > Apply.
If prompted, select Delete from PC.
The wording sounds concerning, but this only removes the iCloud Photos copies from that PC. The photos remain in iCloud and on your other Apple devices. If I remember correctly, you might need to restart the computer before doing the following.
Once iCloud Photos is no longer using the Pictures folder, open:
OneDrive > Settings > Sync and backup > Manage backup
Then enable Pictures folder.