An integrated threat protection solution designed to detect, investigate, and respond to cyber threats across Microsoft 365 services.
hello CT,
This looks like a backend or permission-related issue in Microsoft Defender for Office 365 rather than a browser problem.
Things to check:
Ensure your account has sufficient permissions:
Security Administrator
Global Administrator
Exchange Administrator
Verify the user still exists and is synchronized correctly from Azure AD / Entra ID.
Check if the user is blocked from:
Restricted Entities
Tenant Allow/Block List
Exchange Online Protection
Try removing the restriction using PowerShell instead of the portal.
Check Microsoft 365 service health for any Defender portal incidents: [Microsoft 365 Service Health](https://admin.microsoft.com/Adminportal/Home?utm_source=chatgpt.com#/servicehealth)
If the issue persists for several hours, it is likely a Microsoft-side portal/API issue and opening a Microsoft support ticket is recommended.
You can also try:
Incognito/private mode
Different admin account
Clearing cached Defender session cookies
- Waiting 15–30 minutes after recent policy changes before retrying
hope this will help, have a nice day
thankyou so much