A family of Microsoft spreadsheet software with tools for analyzing, charting, and communicating data.
It depends, are you using the Office apps on a Windows device?
If so, press and hold the Ctrl key on your keyboard when you start Excel to run Excel in Safe Mode, does it open Correctly?
If so, disable any add-ons you may have added to Excel, then check if Excel will open in Normal Mode.
If that does not resolve the problem, the best option is to perform a full repair of your Office installation.
Open the Settings App (gear icon on your Start Menu)
Go to Apps - Installed Apps, then scroll down to find Microsoft Office
Select that and choose Modify - Online Repair
That should fix any issues with your Office Installation.