Processes in Microsoft 365 for setting up Office apps, redeeming product keys, and activating licenses.
Use the following steps to troubleshoot Excel not opening on macOS 26.4.1 with Excel 16.108.3:
- Confirm Excel is installed in the correct location
- When macOS reports that an Office app cannot be opened, verify the application path.
- In the error dialog, check “Problem Details and System Configuration” and note the Path.
- The Office app should be under the main Applications folder (for example,
Macintosh HD\Applications\Microsoft Office 2011or the equivalent modern Office folder). - If Excel (or the Office suite) is in another location, move the whole Office folder back into Applications:
- In Finder, locate the Office folder.
- Select it, then on the Finder menu choose Edit > Copy.
- In Finder, select Go > Applications.
- Choose Edit > Paste Item.
- Try opening Excel again.
- Remove duplicate Excel/Office app entries
- Duplicate app bundles can cause “cannot be opened” errors.
- In Finder, select File > Find and search for Excel.
- In the results, look for multiple Excel application icons.
- If more than one Excel icon appears, select the duplicates and choose File > Move to Trash.
- Empty the Trash, then try opening Excel again.
- If Excel still will not open, completely remove and reinstall Office
- Quit all Office apps.
- In Finder, go to Go > Computer, open Macintosh HD, then Applications.
- Locate the Microsoft Office folder (for your version) and move it to the Trash.
- Reinstall Office for Mac from the source associated with the license (for example, from the Microsoft account’s Services & subscriptions page, or the original installer), then try opening Excel again.
If, after reinstalling, Excel still cannot be opened while other Office apps work, repeat the duplicate-check step and ensure only the newly installed Excel app remains in Applications.
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