A family of Microsoft relational database management systems designed for ease of use.
90+ columns suggests an unnormalized application. You are possibly still thinking “spreadsheet” when you need to model your data in a relational solution.
You can create a table in Access that has a column that matches a unique value in your linked Excel table. Your Access table could be updated as a subform on a from bound to your Excel table.
Bottom line, we need more information about your existing table/fields to provide more quality assistance.