Hi @Alex Kazakou
We are unable to disable the Alt tooltips for the Ribbon completely. But you may try following workaround:
Create a .reg file.
Windows Registry Editor Version 5.00
[HKEY_CURRENT_USER\Software\Policies\Microsoft\office\16.0\word\disabledshortcutkeyslist]
"KeyMod1"="18,4,16"
(Serious problems might occur if you modify the registry incorrectly. Before you modify it, please remember to back up the registry for restoration in case problems occur.
Then double click this .reg file to add the registry key.
There is Microsoft 365 Apps for Enterprise installed on my environment, based on my tests, even if I press another key of the shortcut first, and then press the Alt key, the tooltip will not be triggered.
If the answer is helpful, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment". Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.